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Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.

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Sildenafil protects cyclic guanosine monophosphate (cGMP) from degradation by cGMP-specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum.Sildenafil is broken down in the liver by hepatic metabolism using cytochrome p450 enzymes, mainly CYP450 3A4(major route), but also by CYP2C9 (minor route) hepatic isoenzymes.

See how Viagra fixes erectile dysfunction, what causes the dysfunction and known side effects of Viagra.Methylation of 3-propylpyrazole-5-carboxylic acid ethyl ester with hot dimethyl sulfate.

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Nitric oxide (NO) in the corpus cavernosum of the penis binds to guanylate cyclase receptors, which results in increased levels of cGMP, leading to smooth muscle relaxation ( vasodilation ) of the intimal cushions of the helicine arteries.

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Viagra at The Periodic Table of Videos (University of Nottingham).Trade names include Kamagra ( Ajanta Pharma ), Silagra ( Cipla ), Edegra ( Sun Pharmaceutical ), Penegra ( Zydus Cadila ), and Zenegra ( Alkem Laboratories ).Like Launch Viagra Generic Pills Any Counter There Over Viagra.

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Common side effects include headaches and heartburn, as well as flushed skin.It is used to treat different types of bacterial infections, e.g. bladder inflammation.

The patent on Revatio (indicated for pulmonary arterial hypertension rather than erectile dysfunction) expired in late 2012.Get generic Viagra - a proven medication to cure erectile dysfunction.Viagra is the brand name of the drug sildenafil, which is commonly prescribed to treat erectile dysfunction.Levitra and Viagra now have new campaigns that forego the provocative in favor of depicting erectile dysfunction as a medical condition, not simply a.

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A closer look at flibanserin, the libido-enhancing drug for women that has received US Food and Drug Administration approval.

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Drugs for erectile dysfunction ( G04BE ) and premature ejaculation.Then watch the best of the best free Viagra right now on Redtube.Help About Wikipedia Community portal Recent changes Contact page.

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See also: Drugs for erectile dysfunction and premature ejaculation.