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Intrinsa hit a wall with the FDA when the agency asked for further safety tests over a period of five years.Along with scientists and doctors, hundreds of patients were invited to share their personal experiences of living with the condition.

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The coverage from advocates and nonbelievers has run the gamut—advice, caution, and criticism likely to confuse undecided—but curious—onlookers.

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Every morning, she recorded and quantified her sex life in graphic detail in an e-diary — whether she initiated, used lube, or orgasmed, along with a numerical rating of the experience.

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Men have nine medications on the market to treat erectile dysfunction issues — and more than a dozen others if you include generics and various combinations of treatments.

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The first drug to treat a lack of female sexual desire has been approved by federal authorities.Venezuela is running short on HIV meds—and places to turn for help.By these measures, FDA approved Addyi as the first drug meant to kindle desire.If approved, it will be the first drug authorized by the agency to treat sexual dysfunction in women, compared with nine prescription drugs available for men.Rather than go to sleep after a long day, she gladly stayed up for sex.

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What they said reminded her of arguments used by opponents to antidepressants, who claim that Big Pharma is exploiting people who should be pulling themselves up by their bootstraps.

The results from the latest trials, in 2014, focused on three endpoints: sexual function index (where women answered questions about sexual experience and rated levels of sexual desire on a scale of one to five over the last 28 days), satisfied sexual events, and distress felt from a low libido.While a testosterone patch for women was tested in 2004, it never made it to the U.S. market. A handful of other hormonal and non-hormonal drugs owned by small companies are now at various stages of clinical testing.

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Women on the drug showed a 37% boost in sexual desire, a 37% increase in satisfying sexual events, and a 21% decrease in sexual distress, and all of these were significantly different than the results of the placebo group.

Her doctor asked about the obvious culprits: her full-time job, her six kids, the predictable dimming of the post-honeymoon period.In the years since, flibanserin has sparked a national debate over the nature of female sexuality.One woman — who was not diagnosed with HSDD — stood up to the podium and listed the various ways she had overcome her low sex drive — without any help from a pharmaceutical drug.In a 2011 paper in The Journal of Sexual Medicine that reviews previous studies of its mechanisms, they explain it in this way: Serotonin, which is thought to impede sexual interest, has two types of receptors in the brain. 5-HT1A acts like brakes for serotonin production, and 5-HT2A accelerates production.These extra tests would have cost too much, so the company abandoned the U.S. market altogether.They work by increasing blood flow all over the body, including to the genitals, helping.

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Sign up to receive an email from The New York Times as soon as important news breaks around the world.The new libido pill will likely lure users for whom it was not approved: women taking antidepressants.Scanlan also points to Europe, where until 2012 a testosterone treatment called Intrinsa was widely available for women with low libido.

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The libido enhancement drug flibanserin (trade name Addyi) took center stage last week after winning long-sought approval from the U.S. Food and Drug Administration (FDA).This week health experts officially approved the first female libido booster, flibanserin.But there was a strong placebo effect as well: The e-diary scores of sexual desire were no different in women taking flibanserin and those taking sugar pills.But FDA twice concluded that the resulting increases in libido were not statistically significant, and regulators were wary of potentially dangerous side effects like dizziness, sleepiness, nausea, and fainting.